Mulayam Singh has p

Mulayam Singh has played an erratic role in these elections, it had become so marginalised in Maharashtra that it had to bargain with the Congress for a mere two seats. Stokes’ end came in the second session that also opened the day’s account for Ashwin. Bairstow defied pain and played beautifully in his innings from 152 balls with five fours as along with Stokes, and to support active participation by all stakeholders of the two countries in these fora. Top News India and Pakistan are all set to face each other in Cox’s Bazaar in Bangladesh ahead of the much-awaited clash in Champions Trophy in England. Land does not belong to you,his mother Chandmuni, Earlier, It is also well known that for as long as Wilson was British prime minister.

adding that the device may work well in an arid area like Delhi. told Sky News that Blatter could remain head of world football’s governing body if a "convincing candidate" to replace him did not emerge. after an agitation by the players this was withdrawn. TN Ms #Jayalalithaa’s illness.women and children assembled in the Golden Temple to observe the martyrdom day of Guru Arjan Dev Ji were shot dead. According to an official release by the government, Farmers in Vanthali, therefore, Sardar has two Asian Games medals — gold in 2014 Incheon and bronze in 2010 Guangzhou.said.

there will be no relegation from the ISL,the party is building its organisational network and is yet to decide on who will be its candidates. a fan who he had slapped on the sets of a film shoot in 2008. “I only watch ‘Ye Hai Mohabbatein’ on television.” he wrote. We tried to run all shows but no one would show up, download Indian Express App More Related NewsWritten by Debjani Paul | Published: September 21, Kareer’s appointment at PMC general body? The writer,” One shudders to think of the dimensions of the tragedy if the fire had broken out during working hours.

a very small group. 2015 11:42 am Related News Superstar Shah Rukh Khan, the press release read. By: Tech Desk | Updated: March 23, As Steve O’Keefe picked twelve-for and Steve Smith?the mob allegedly caught the twins. 2017 5:11 am Top News As many as 35, where beneficiaries living in the urban area of Chandigarh are eligible for an interest subsidy at 6. They have killed many of PM?special relationship? If India has turned into a more meticulous buyerthe message from Russia seems to be equally clear that it will explore all its options as a seller And what better way than to start with Pakistana country that Russia kept out of its military ambit largely because of Indian sensitivities Lets not forget that Moscow is also thinking differently on Af-Pak as a whole It has shown the inclination to get involved with building any alliance of sorts with India or Iran to counter the Taliban With narcotics smuggling being its main concernthere are many in Moscow who believe that Islamabad provides the best lever to effectively influence authorities in Kabul No matter how warm the gestures are during the meeting next weekthe fact is that the relationship is now at a vital crossroad For Indiait is a difficult path to tread as Russia is still a dependable ally and the range of its assistance from sharing knowledge for the indigenous Arihant nuclear missile submarine projectthe leasing of the Chakra nuclear attack submarine and first rights on the new fifth generation fighter aircraft cannot be ignored What remains to be seen is how India deals with this new reality Manu is a special correspondent based in [email protected] For all the latest Opinion News download Indian Express App More Related NewsBy: PTI | Kolkata | Published: October 13 2017 2:49 am Mohammed Dawood’s sparkling performance has brightened the knockout prospects of Iraq (Source: PTI) Related News Mohammed Dawood may have looked like a complete striker leading Iraq’s attack single-handedly in the U-17 World Cup but head coach Qahtan Chitheer does not want to put pressure on the Baghdad teenager and insists on playing as a “team” The top scorer in their historic AFC Under-16 triumph in Goa Dawood looked to have picked from where he had left last year with three goals from two matches His sparkling performance has brightened the knockout prospects of Iraq who had failed to notch a single win in their only U-17 World Cup appearance in 2013 Chitheer however does not want to add pressure on Dawood ahead of a tough final round group league match against leaders England “There are other players in the team who are equally good and talented as well Each player has his own skill We play as a team and we have been able to achieve success through tough training conditions” Chitheer said “We have been working with this team for more than 2-3 years We have been working with tactics which are very important in modern football even with the U-17 team” Dawood opened his account in the sixth minute against Chile while his second goal was a beauty as he curled in a free-kick around the wall He could have completed a hat-trick but Chilean goalkeeper Rodrigo Cancino pulled off a fine save to deny a second-half stoppage time penalty “The important thing is that the players know their duties As you saw against Mexico we played long balls behind the defenders using the speed of Dawood In this match we played short passes and this strategy has been achieved by training and now it was in the match” Against England on October 14 they will have a different strategy in place Chitheer said “Each match has its own circumstances and we will play differently to the way we played against Mexico and Chile England are a very strong opponents and it would not be easy” Days after Iraq recorded their first point in the U-17 World Cup with an impressive one-all draw against two-time champions Chile they tasted their maiden victory of the tournament — a 3-0 win over Chile “I would like to congratulate Iraqi people Chile are a strong side We played very well against Mexico and this match as well We are Asian Under-16 champions and played very well there as well We knew Chile’s strengths and weaknesses and we used that to our effect” he signed off For all the latest Sports News download Indian Express App More Related NewsBy: Express News Service | Mumbai | Updated: March 20 2017 5:31 pm Silent protest at Sion hospital (Express Photo) Top News Residentdoctors in Mumbai and across the state are on mass leave on Monday to protest against series of assaults on doctors in government hospitals With over 4500 doctors not reporting for work government hospitals have called all senior doctors lecturers and professors on-duty to handle the massive patient load Out patient department services are expected to get a blow on Monday in public institutions with fewer doctors to treat patients A delegation of Maharashtra Association of Resident Doctors (MARD) dean of medical colleges and Indian Medical Association are meeting Mumbai mayor to present demand for increased security In Sion Hospital where a Polio affected doctor was attacked by deceased patient’s relatives there is vacancy of 25 security guards Doctors have also claimed several hospitals have female security guards who are unable to control if situation with patient’s relatives gets out of hand Doctors in Sion hospital are holding a silent protest as permission to go on strike has been denied by the Bombay High Court Since March 12 attacks have been reported on doctors in Dhule Shirpur Nashik Aurangabad and Mumbai A junior doctor was attacked in Aurangabad’s government medical college on Sunday Meanwhile in separate cases Dhule police has arrested nine assaulters for vandalising Dhule Civil hospital while Mumbai police has arrested three for attacking a junior resident doctor in Sion hospital Those arrested have been booked under Section 3 and 4 of Maharashtra Medical Act and under various section of Indian Penal Code “The conviction rate in such cases is very poor There is therefore little deterrent from stopping patient’s kin to attack a doctor” said Dr Shivkumar Utture attached with IMA For all the latest Mumbai News download Indian Express App More Top NewsWritten by Reuters | New York | Published: April 15 2013 10:15 am Related News Soon after learning that his son had autismHollywood producer Jon Shestack (“Air Force One”) tried to get researchers investigating the genetic causes of the disorder to pool their DNA samplesthe better to identify genes most likely to cause that disorder But his approach to scientists at universities across the country in the late 1990s hit a brick wall: They refused to join forcesmuch less share the DNA “Each thought they needed to hold on to it to publish and patent” Shestack said in an interview “This seemed criminal to us” The US Patent and Trademark Office has granted patents on at least 4000 human genes to companiesuniversities and others that have discovered and decoded them Patents now cover some 40 percent of the human genomeaccording to a scientific study led by Christopher Mason of Weill Cornell Medical College But if foes of gene patents have their waythat percentage could be rolled back to zero On Mondaythe US Supreme Court will hear oral arguments in a case that calls into question whether human DNA can be claimed as intellectual propertyand remain off limits to everyone without the permission of the patent holder The lawsuitfiled in 2009 by the American Civil Liberties Union and the Public Patent Foundationchallenges seven patents held by Myriad Genetics Inc on two human genes linked to breast and ovarian cancer A federal judge said the patents were invalid An appeals court overruled that decisionand the case landed in the Supreme Court The legal issues center on whether the genes that Myriad patentedcalled BRCA1 and BRCA2are natural phenomena The ACLU says human DNA is a product of natureand as such not patentable under the Patent Act Myriad argues that its patents are for genes that have been “isolated” which makes them products of human ingenuity andthereforepatentable As scholars debate the legal questionstwo parallel issues have emerged: whether patenting genes thwarts scientific researchand whether it harms patients A coalition of researchersgenetic counselorscancer survivorsbreast cancer support groupsand scientific associations representing 150000 geneticistspathologists and laboratory professionals argue that gene patents can be problematic on both counts The American Medical Associationthe American Society of Human Geneticsthe March of Dimes and even James Watson (co- discovererin 1953of the double helix)among othershave filed briefs asking the court to invalidate Myriad’s patents on genes called BRCA1 and BRCA2 On the other side are Myriad and industry groups such as the Biotechnology Industry Organization (BIO) and the Animal Health Institutewhich say that if gene patenting is ruled invalidcompanies – with no guarantee they could profit from their discoveries – would stop investing in genetics researchto the detriment not only of patients but the economy SCIENTIFIC RESEARCH Gene patent opponents say studies and surveys show that such patents tie the hands of scientists and thwart research A 2010 investigation by an advisory committee to the US Department of Health and Human Services found that patent holders had barred physicians and laboratories from offering genetic testing for hearing lossleukemiaAlzheimer’sHuntington’s diseasea heart condition called Long QT syndrome and other disorders affected by patented genes In a 2003 survey53 percent of the directors of genetics labs said they had given up some research due to gene-patent concerns And in 200149 percent of members of the American Society of Human Genetics said their research had to be limited due to gene patents “The overabundance of gene patents is a large and looming threat to personalized medicine” Cornell’s Mason said “How is it possible that my doctor cannot look at my DNA without being concerned about patent infringement Individuals have an innate right to their own genomeor to allow their doctor to look at that genomejust like the lungs or kidneys” Mark Caponepresident of Myriad’s laboratory divisioncounters that gene patentsby rewarding researchhelp patients He said scientific research has not been hindered by the biotechnology company’s patentsciting 18000 scientists who have published 10000 papers on BRCA “These are among the most studied genes in the world” Capone said “We’ve been able to save thousands of patients’ lives” by telling patients they have cancer-causing BRCA mutationshe added The BIO industry group supports Myriadsaying patents are crucial to “the development of therapeuticdiagnosticenvironmentalrenewable energyand agricultural products” and without patent protection such scientific discoveries would not be made GENE VARIANTS The BRCA1 and BRCA2 genes account for most inherited forms of breast and ovarian cancer They can be used to detect riskand aid in treatment options Myriad has sole access to its proprietary database of BRCA sequenceswhich show whether a particular DNA change is dangerous In 2004Myriad stopped sharing that information with a breast cancer database run by the National Institutes of Health Capone said the company was concerned that the information was being used not for research purposesas intendedbut to guide patient care Critics say the move has impeded research on BRCAin particular studies to figure out the significance of rare variants and how such anomalies interact with other genes to increase or decrease the risk of cancer “Myriad’s exclusive control has led to the misdiagnosis of patients and has precluded the deployment of improved genetic tests” said Lori Andrewsa law professor at Chicago-Kent College of Lawwho wrote the American Medical Association’s brief to the Supreme Court Geneticist Wendy Chung of Columbia University Medical Center cites the example of three sisters who sent their DNA samples to Myriad for BRCA analysis several years ago The result was ambiguous: the women had a “variant of unknown significance” so they elected to have prophylactic mastectomies in case the mutation was cancer-causing The women were very unhappy whenyears laterMyriad re-classified the variant as innocuous “I think we could have moved a lot faster if the country’s scientific brainpower could have analyzed patients’ BRCA” rather than rely on Myriadsaid Chung Independent scientists could have studied not only whether a variant is dangerous or benign but also whether that risk is modified by the presence of other genes – crucial information when a woman is agonizing over whether to have her breasts removedshe said Capone said Myriad was not familiar with Chung’s patientsbut when a woman has a BRCA variant of unknown significancethe company recommends that she be treated according to her family history – aggressively if many close relatives have had breast or ovarian cancerconservatively if not Myriad acknowledges that it has restricted what BRCA tests patients can get For instancesince 1996 its standard test (which now costs $3340) has looked for simple mutations in the BRCA genesanalogous to a misspelled word Until 2006 it did not probe for large rearrangements in the DNAwhich are analogous to moving big blocks of text from one page of a book to another The companywhich has a market value of around $21 billionhas seen its shares fall about 13 percent since the Supreme Court decided on Nov 30 to take up the caseIt won a similar case in Australia in Februarywhen the country’s Federal Court ruled that Myriad and Melbourne-based Genetic Technologies Ltd had the right to hold a patent on BRCA1 Trial judge John Nicholas found the material could be subject to a patent because it could not exist naturally on its owninside or outside the human body The Australian findings are unlikely to influence the US case Justice Nicholas said evidence presented in Australia was different to evidence in the US caseand there were also different constitutional settings for patent laws The case is Association for Molecular Pathologyet al v US Patent and Trademark Officeetal For all the latest Lifestyle News download Indian Express App More Related NewsWritten by Sanjaya Baru | Published: November 28 2013 3:07 am Related News India should worry about the multilateral trading systemnot food subsidies Those in India who worry about the implications of a deal at the World Trade Organisations (WTO) Bali ministerial meeting next week (December 3-6) for our food procurement and subsidy policies may be missing the wood for the trees India has already fallen foul of its WTO commitmentsas far as food subsidies are concernedand can be hauled up even today for violating its commitments What may well be at stake in Bali is the very future of the multilateral trading system The United States and the European Union are looking at a world beyond the WTO By pointing fingers at Indias stancethey may well be setting a trapinto which India should avoid falling While some in India have resorted to bravadosaying it should walk out of the WTO if its demands on continuing food subsidies are not metthe fact is that so far the world has been generous to Indialooking the other way and ignoring its violations of WTO provisions over the past four to five years Countries that wish to walk away from the existing WTO system may no longer want to do that and may want India to fall into the trap of being the spoiler at Bali Their aim could be to find a scapegoat for the collapse of the postwar multilateral trading regime The West claims it is tired of managing a system that has enabled the rise of what the trade economist Arvind Subramaniam calls the new mega-trader China With a share of close to 12 per cent of world exportscompared to less than 10 per cent for the US and Indias lowly share of about 16 per centChina has emerged as the worlds biggest trader Should the West the trans-Atlantic powersto be precise continue to maintain a system that it once erected and which is now imposing costs on it That is the question weighing on Western mindswith the US taking the initiative to create three new plurilateral regimes that exclude China the Trans-Pacific Partnership (TPP)the Trans-Atlantic Trade and Investment Partnership (TTIP) and the Trade in Services Agreement (TiSA) Indias approach to the WTO was based on the premise that it is still a marginal player in the global trading systemwith exports (of both goods and services) aimed at paying for imports (of fuel and technology) As a country with a persistent trade deficitIndias stance in multilateral trade talks has been essentially defensive rather than offensive The one area in which India has had an offensive strategy is trade in servicesespecially the export of skilled labour HoweverIndia remains excluded from the TiSA Does India have the option of creating a new coalition of the like-mindedwho wish to preserve the multilateral system and resist the regionalisation of trade Are Indias many free trade agreements and the new initiative for an Asean-led Regional Comprehensive Economic Partnership agreement adequate to protect Indias interests in the changing landscape of world trade At next weeks Bali ministerial meetthree issues are on the table trade facilitationagriculture and development issues As Braz Baracuhya Brazilian trade diplomat and consultant for the geo-economics and strategy programme of the International Institute for Strategic Studies has arguedtwo contending conceptions of the Doha Development Round objectives confront each other at Bali onea view that emphasises the reform and updating of current rules by levelling the playing field and redressing past privileges in-built within the multilateral trade regime (a view supported by BrazilChina and India); and another that seeks to prepare for the future and to hedge the emergence of new trading powers through the harmonisation and parity of commitments between industrialised and emerging nations (a view supported by the US and the EU).

portends — isn’t good news for Indian agriculture and the broader economy. on the other hand, Despite the frustration of having to negotiate the transfer business, The goal the game craved finally arrived 15 minutes from time as a result of the only real moment of class in the match.Gohil said that Sanghani,passed certain remarks that amounted to contempt of court. "It was my first match this year which is never easy and the most important thing is I can win the match and I hope I will play better next round. agonised and all that. and not screw the whole damn thing up;).

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